Manufacturing Differences on Physicochemical and In Vitro Release Characteristics of Semisolid Ophthalmic Ointments
نویسندگان
چکیده
منابع مشابه
Synthesis of Metformin Hydrochloride nanoliposomes: Evaluation of physicochemical characteristics and release kinetics
Metformin hydrochloride, a drug group of biguanides, with significant efficacy in the treatment of diabetes type II, is decomposed before reaching to the stomach and is wasted in great losses. In this study, the nanoliposomes of metformin hydrochloride were prepared with Bingham method. At first, the single factor test is done. Design variables are: lecithin to cholesterol ratio, organic solven...
متن کاملSynthesis of Metformin Hydrochloride nanoliposomes: Evaluation of physicochemical characteristics and release kinetics
Metformin hydrochloride, a drug group of biguanides, with significant efficacy in the treatment of diabetes type II, is decomposed before reaching to the stomach and is wasted in great losses. In this study, the nanoliposomes of metformin hydrochloride were prepared with Bingham method. At first, the single factor test is done. Design variables are: lecithin to cholesterol ratio, organic solven...
متن کاملNorfloxacin and metronidazole topical formulations for effective treatment of bacterial infections and burn wounds.
INTRODUCTION Our various previous findings have shown the suitability of norfloxacin in the treatment of bacterial infections and burn wounds in alone as well as in combination with Curcuma longa in various topical (ointments, gels, and creams) and transdermal drug delivery systems. AIMS AND METHODS Keeping these facts in consideration, we have made an another attempt to prepare semisolid for...
متن کاملDesign and Evaluation of Ocular Controlled Delivery System for Diclofenac Sodium
Diclofenac sodium as ophthalmic dosage form is used in patients treatment of eye pain, swelling and redness recovering from cataract surgery but it faces the bioavailability limitation of eye drops due to effective protective mechanisms and corneal barrier functions in the eyes. Therefore, this investigation was aimed to develop ocular film formulations to achieve controlled drug release. Drug ...
متن کاملEfficacy and Physicochemical Evaluation of an Optimized Semisolid Formulation of Povidone Iodine Proposed by Extreme Vertices Statistical Design; a Practical Approach
One of the most significant issues in pharmaceutical industries, prior to commercializationof a pharmaceutical preparation is the “preformulation” stage. However, far too attention hasbeen paid to verification of the software assisted statistical designs in preformulation studies.The main aim of this study was to report a step by step preformulation approach for a semisolidpreparation based on ...
متن کامل